BDBM50044876 (4aR,10bR)-4-Methyl-1,4,4a,5,6,10b-hexahydro-2H-benzo[f]quinolin-3-one::4-Methyl-1,4,4a,5,6,10b-hexahydro-2H-benzo[f]quinolin-3-one::CHEMBL57789

SMILES CN1[C@@H]2CCc3ccccc3[C@H]2CCC1=O

InChI Key InChIKey=GREXNIICGIQJBG-CHWSQXEVSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50044876   

Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
University of Canterbury

Curated by ChEMBL
LigandPNGBDBM50044876((4aR,10bR)-4-Methyl-1,4,4a,5,6,10b-hexahydro-2H-be...)
Affinity DataIC50:  560nMAssay Description:In vitro inhibitory activity against Steroid 5-alpha-reductase type IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
University of Canterbury

Curated by ChEMBL
LigandPNGBDBM50044876((4aR,10bR)-4-Methyl-1,4,4a,5,6,10b-hexahydro-2H-be...)
Affinity DataIC50:  562nMAssay Description:In vitro inhibitory concentration required to inhibit Steroid 5-alpha-reductase type 1 in cultured Hs 68 human foreskin fibroblast cellsMore data for this Ligand-Target Pair
In DepthDetails Article
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
University of Canterbury

Curated by ChEMBL
LigandPNGBDBM50044876((4aR,10bR)-4-Methyl-1,4,4a,5,6,10b-hexahydro-2H-be...)
Affinity DataIC50:  560nMAssay Description:In vitro inhibition of DHT production in Hs 68 (human genital fibroblast) cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed