BDBM50046266 2-[2-(2-Benzyl-3-mercapto-butyrylamino)-3-methyl-pentanoylamino]-3-(4-hydroxy-phenyl)-propionic acid::CHEMBL172978

SMILES CCC(C)C(NC(=O)C(Cc1ccccc1)C(C)S)C(=O)NC(Cc1ccc(O)cc1)C(O)=O

InChI Key InChIKey=CLFZKEZRSHMJQM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50046266   

TargetAngiotensin-converting enzyme(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50046266(2-[2-(2-Benzyl-3-mercapto-butyrylamino)-3-methyl-p...)
Affinity DataIC50: 300nMAssay Description:Inhibitory concentration was evaluated by inhibiting 50% of Angiotensin I Converting Enzyme activity using 50 uM N-Cbz-Phe-His-Leu as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeprilysin(Rabbit)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50046266(2-[2-(2-Benzyl-3-mercapto-butyrylamino)-3-methyl-p...)
Affinity DataIC50: 380nMAssay Description:Inhibitory concentration was evaluated by Inhibiting 50% of Neutral endopeptidase enzyme (NEP) activity using 20 nM [3H]D-Ala2-Leu-enkephalin as subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed