BDBM50046813 4-[2-(2-tert-Butoxycarbonylamino-3,3-dimethyl-butyrylamino)-3-methyl-pentanoylamino]-3-hydroxy-6-methyl-heptanoic acid::CHEMBL343681

SMILES CCC(C)C(NC(=O)C(NC(=O)OC(C)(C)C)C(C)(C)C)C(=O)NC(CC(C)C)C(O)CC(O)=O

InChI Key InChIKey=YFYJTMYWPJCXPG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50046813   

TargetEndothelin-converting enzyme 1(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50046813BDBM50046813(4-[2-(2-tert-Butoxycarbonylamino-3,3-dimethyl-buty...)
Affinity DataIC50: 750nMAssay Description:Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed
TargetCathepsin D(Bovine)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50046813BDBM50046813(4-[2-(2-tert-Butoxycarbonylamino-3,3-dimethyl-buty...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of conversion of hemoglobin by commercially purchased bovine spleen cathepsin D.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50046813BDBM50046813(4-[2-(2-tert-Butoxycarbonylamino-3,3-dimethyl-buty...)
Affinity DataIC50: 1.00E+4nMpH: 6.0Assay Description:In vitro inhibition of partially purified human renin at pH 6.0.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed