BDBM50047461 Benzyl-((2E,6E)-3,7,11-trimethyl-dodeca-2,6,10-trienyl)-amine::Benzyl-(3,7,11-trimethyl-dodeca-2,6,10-trienyl)-amine::CHEMBL37505

SMILES [#6]\[#6](-[#6])=[#6]/[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#7]-[#6]-c1ccccc1

InChI Key InChIKey=PRWFDAYIIGXVQN-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50047461   

TargetSqualene synthase(Rat)
Sandoz Research Institute

Curated by ChEMBL
LigandPNGBDBM50047461(Benzyl-((2E,6E)-3,7,11-trimethyl-dodeca-2,6,10-tri...)
Affinity DataIC50: 10nMAssay Description:Tested for inhibitory activity against squalene synthetase in the presence of inorganic pyrophosphate (PPi)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Sandoz Research Institute

Curated by ChEMBL
LigandPNGBDBM50047461(Benzyl-((2E,6E)-3,7,11-trimethyl-dodeca-2,6,10-tri...)
Affinity DataIC50: 100nMAssay Description:Tested for the squalene synthetase inhibitory activity in rat liver microsomal assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetSqualene synthase(Rat)
Sandoz Research Institute

Curated by ChEMBL
LigandPNGBDBM50047461(Benzyl-((2E,6E)-3,7,11-trimethyl-dodeca-2,6,10-tri...)
Affinity DataIC50: 100nMAssay Description:Compound was tested for inhibitory activity against squalene synthase using rat liver microsomal assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetSqualene synthase(Rat)
Sandoz Research Institute

Curated by ChEMBL
LigandPNGBDBM50047461(Benzyl-((2E,6E)-3,7,11-trimethyl-dodeca-2,6,10-tri...)
Affinity DataIC50: 100nMAssay Description:Inhibitory activity against squalene synthetase in rat liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed