BDBM50048718 CHEMBL3317473

SMILES CC(Nc1ccc(Cl)cc1)c1cc(cn2c1nc(cc2=O)N1CCOCC1)C(=O)NCCN(C)C

InChI Key InChIKey=YXYLJVDEKYPHBA-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50048718   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
Astrazeneca

Curated by ChEMBL

LigandBDBM50048718(CHEMBL3317473)Copy SMILESCopy InChI

Affinity DataIC50: 75nMAssay Description:Inhibition of PI3Kbeta in human MAD-MB-468 cells assessed as inhibition of Ser473 Akt phosphorylation by cellular potency assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
3/25/2016
Entry Details Article
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