BDBM50049345 CHEMBL423824::N-[1-{[Acetyl-(3-methoxy-benzyl)-amino]-methyl}-2-(1H-indol-3-yl)-ethyl]-2-(4-phenyl-piperazin-1-yl)-acetamide

SMILES COc1cccc(CN(CC(Cc2c[nH]c3ccccc23)NC(=O)CN2CCN(CC2)c2ccccc2)C(C)=O)c1

InChI Key InChIKey=UEMMIMGZPQLHRL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50049345   

TargetSubstance-P receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50049345(N-[1-{[Acetyl-(3-methoxy-benzyl)-amino]-methyl}-2-...)
Affinity DataIC50: 4.60nMAssay Description:Inhibitory activity against Tachykinin receptor 1 in human IM-9 cells using [125I]-labeled Boltan-Hunter substance P as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed