BDBM50049488 5-Bromo-2-((1S,5R)-5-hydroxy-2,2,5-trimethyl-6-methylene-cyclohexylmethyl)-4-methoxy-phenol::CHEMBL50534

SMILES COc1cc(C[C@@H]2C(=C)[C@](C)(O)CCC2(C)C)c(O)cc1Br

InChI Key InChIKey=NTUAVXWCKQEOJQ-FZKQIMNGSA-N

Data  3 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50049488   

TargetProgesterone receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50049488(5-Bromo-2-((1S,5R)-5-hydroxy-2,2,5-trimethyl-6-met...)
Affinity DataKi:  275nMAssay Description:Binding affinity determined for human Progesterone receptor A isoformMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50049488(5-Bromo-2-((1S,5R)-5-hydroxy-2,2,5-trimethyl-6-met...)
Affinity DataKi:  6.66E+3nMAssay Description:Binding affinity determined against human Androgen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50049488(5-Bromo-2-((1S,5R)-5-hydroxy-2,2,5-trimethyl-6-met...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity was determined for human glucocorticoid receptor(hGR).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50049488(5-Bromo-2-((1S,5R)-5-hydroxy-2,2,5-trimethyl-6-met...)
Affinity DataIC50:  2.00E+3nMAssay Description:Concentration required to give half-maximal inhibition against human Progesterone receptor B isoform in co-transfected CV-1 cell lines.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50049488(5-Bromo-2-((1S,5R)-5-hydroxy-2,2,5-trimethyl-6-met...)
Affinity DataIC50:  430nMAssay Description:Antagonistic potency to the human progesterone receptor measured in the T-47D alkaline phosphatase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed