BDBM50049489 Acetic acid 5-bromo-4-methoxy-2-((S)-3,6,6-trimethyl-2-methylene-cyclohex-3-enylmethyl)-phenyl ester::CHEMBL50619

SMILES COc1cc(C[C@@H]2C(=C)C(C)=CCC2(C)C)c(OC(C)=O)cc1Br

InChI Key InChIKey=ZVQZJGGVFKLMKX-MRXNPFEDSA-N

Data  3 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50049489   

TargetProgesterone receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50049489(Acetic acid 5-bromo-4-methoxy-2-((S)-3,6,6-trimeth...)
Affinity DataKi:  455nMAssay Description:Binding affinity determined for human Progesterone receptor A isoformMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50049489(Acetic acid 5-bromo-4-methoxy-2-((S)-3,6,6-trimeth...)
Affinity DataKi:  4.11E+3nMAssay Description:Binding affinity was determined for human glucocorticoid receptor(hGR).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50049489(Acetic acid 5-bromo-4-methoxy-2-((S)-3,6,6-trimeth...)
Affinity DataKi:  6.39E+3nMAssay Description:Binding affinity determined against human Androgen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50049489(Acetic acid 5-bromo-4-methoxy-2-((S)-3,6,6-trimeth...)
Affinity DataIC50:  210nMAssay Description:Antagonistic potency to the human progesterone receptor measured in the T-47D alkaline phosphatase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50049489(Acetic acid 5-bromo-4-methoxy-2-((S)-3,6,6-trimeth...)
Affinity DataIC50:  660nMAssay Description:Concentration required to give half-maximal inhibition against human Progesterone receptor B isoform in co-transfected CV-1 cell lines.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed