BDBM50049492 5-Bromo-4-methoxy-2-[(E)-3-(4,6,6-trimethyl-2-methylene-cyclohex-3-enyl)-propenyl]-phenol::CHEMBL49978

SMILES COc1cc(\C=C\CC2C(=C)C=C(C)CC2(C)C)c(O)cc1Br

InChI Key InChIKey=HBEGIVRBESAQLK-VOTSOKGWSA-N

Data  3 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50049492   

TargetProgesterone receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50049492(5-Bromo-4-methoxy-2-[(E)-3-(4,6,6-trimethyl-2-meth...)
Affinity DataKi:  84nMAssay Description:Binding affinity determined for human Progesterone receptor A isoformMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50049492(5-Bromo-4-methoxy-2-[(E)-3-(4,6,6-trimethyl-2-meth...)
Affinity DataKi:  2.32E+3nMAssay Description:Binding affinity determined against human Androgen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50049492(5-Bromo-4-methoxy-2-[(E)-3-(4,6,6-trimethyl-2-meth...)
Affinity DataKi:  4.42E+3nMAssay Description:Binding affinity was determined for human glucocorticoid receptor(hGR).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50049492(5-Bromo-4-methoxy-2-[(E)-3-(4,6,6-trimethyl-2-meth...)
Affinity DataEC50:  3.30E+3nMAssay Description:Effective concentration against human Progesterone receptor B isoform expressed in CV-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50049492(5-Bromo-4-methoxy-2-[(E)-3-(4,6,6-trimethyl-2-meth...)
Affinity DataIC50:  1.60E+3nMAssay Description:Antagonistic potency to the human progesterone receptor measured in the T-47D alkaline phosphatase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed