BDBM50049495 5-(4,6,6-Trimethyl-2-methylene-cyclohex-3-enylmethyl)-benzo[1,2,5]oxadiazole::CHEMBL50786

SMILES CC1=CC(=C)C(Cc2ccc3nonc3c2)C(C)(C)C1

InChI Key InChIKey=TXUCEYPUSCJMMT-UHFFFAOYSA-N

Data  3 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50049495   

TargetProgesterone receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50049495(5-(4,6,6-Trimethyl-2-methylene-cyclohex-3-enylmeth...)
Affinity DataKi:  88nMAssay Description:Binding affinity determined for human Progesterone receptor A isoformMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50049495(5-(4,6,6-Trimethyl-2-methylene-cyclohex-3-enylmeth...)
Affinity DataKi:  8.36E+3nMAssay Description:Binding affinity was determined for human glucocorticoid receptor(hGR).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50049495(5-(4,6,6-Trimethyl-2-methylene-cyclohex-3-enylmeth...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity determined against human Androgen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50049495(5-(4,6,6-Trimethyl-2-methylene-cyclohex-3-enylmeth...)
Affinity DataIC50:  775nMAssay Description:Antagonistic potency to the human progesterone receptor measured in the T-47D alkaline phosphatase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50049495(5-(4,6,6-Trimethyl-2-methylene-cyclohex-3-enylmeth...)
Affinity DataIC50:  1.95E+3nMAssay Description:Concentration required to give half-maximal inhibition against human Progesterone receptor B isoform in co-transfected CV-1 cell lines.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed