BDBM50049588 6-{[Methyl-(3,4,5-trichloro-phenyl)-amino]-methyl}-pyrido[3,2-d]pyrimidine-2,4-diamine::CHEMBL52698

SMILES CN(Cc1ccc2nc(N)nc(N)c2n1)c1cc(Cl)c(Cl)c(Cl)c1

InChI Key InChIKey=FVRDUZOKYWZFLL-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50049588   

TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50049588(6-{[Methyl-(3,4,5-trichloro-phenyl)-amino]-methyl}...)
Affinity DataIC50: 38nMAssay Description:Inhibition of Toxoplasma gondii dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50049588(6-{[Methyl-(3,4,5-trichloro-phenyl)-amino]-methyl}...)
Affinity DataIC50: 38nMAssay Description:Inhibitory activity against Toxoplasma gondii dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50049588(6-{[Methyl-(3,4,5-trichloro-phenyl)-amino]-methyl}...)
Affinity DataIC50: 87nMAssay Description:Inhibitory activity against rat liver dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50049588(6-{[Methyl-(3,4,5-trichloro-phenyl)-amino]-methyl}...)
Affinity DataIC50: 87nMAssay Description:Inhibition of rat liver dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Baker's yeast)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50049588(6-{[Methyl-(3,4,5-trichloro-phenyl)-amino]-methyl}...)
Affinity DataIC50: 250nMAssay Description:Inhibitory activity against Pneumocystis carinii dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50049588(6-{[Methyl-(3,4,5-trichloro-phenyl)-amino]-methyl}...)
Affinity DataIC50: 250nMAssay Description:Inhibition of Pneumocystis carinii dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed