BDBM50049591 6-{[Methyl-(2,4,6-trichloro-phenyl)-amino]-methyl}-pyrido[3,2-d]pyrimidine-2,4-diamine::CHEMBL52930

SMILES CN(Cc1ccc2nc(N)nc(N)c2n1)c1c(Cl)cc(Cl)cc1Cl

InChI Key InChIKey=RQTLSQCDNIJYOU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50049591   

TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50049591(6-{[Methyl-(2,4,6-trichloro-phenyl)-amino]-methyl}...)
Affinity DataIC50: 44nMAssay Description:Inhibitory activity against Toxoplasma gondii dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50049591(6-{[Methyl-(2,4,6-trichloro-phenyl)-amino]-methyl}...)
Affinity DataIC50: 52nMAssay Description:Inhibitory activity against rat liver dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Baker's yeast)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50049591(6-{[Methyl-(2,4,6-trichloro-phenyl)-amino]-methyl}...)
Affinity DataIC50: 120nMAssay Description:Inhibitory activity against Pneumocystis carinii dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed