BDBM50050084 CHEMBL3317834::US9216988, 32

SMILES COC(=O)N1CCN(CC1)c1ccc(CN(CC(C)C)S(=O)(=O)Cc2ccccc2)cc1

InChI Key InChIKey=PFPGPDIWXXIYIX-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50050084   

TargetNuclear receptor ROR-gamma(Human)
Genentech

US Patent
LigandPNGBDBM50050084(US9216988, 32 | CHEMBL3317834)
Affinity DataIC50: 285nMpH: 7.4Assay Description:On day of the assay, 100 uL of 0.05% CHAPS (in deionized H2O) was added to all wells of the GFB Unifilter plate and allowed soak for 1 h. A wash buff...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Genentech

US Patent
LigandPNGBDBM50050084(US9216988, 32 | CHEMBL3317834)
Affinity DataEC50:  310nMAssay Description:Inverse agonist activity at N-terminal 6xHis-tagged human RORc ligand binding domain (241 to 486) expressed in bacterial expression system assessed a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2016
Entry Details Article
PubMed