BDBM50050464 3-(4-Phenyl-piperazin-1-ylmethyl)-1H-indole::CHEMBL59324

SMILES C(N1CCN(CC1)c1ccccc1)c1c[nH]c2ccccc12

InChI Key InChIKey=FDOZNCJWYJMHAG-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50050464   

TargetD(4) dopamine receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50050464(3-(4-Phenyl-piperazin-1-ylmethyl)-1H-indole | CHEM...)
Affinity DataKi:  8nMAssay Description:Binding affinity towards cloned human Dopamine receptor D4 stably expressed in CHO cells was evaluated using [3H]spiperone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50050464(3-(4-Phenyl-piperazin-1-ylmethyl)-1H-indole | CHEM...)
Affinity DataKi:  8nMAssay Description:Binding affinity towards human dopamine receptor D4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50050464(3-(4-Phenyl-piperazin-1-ylmethyl)-1H-indole | CHEM...)
Affinity DataKi:  120nMAssay Description:Binding affinity towards cloned human Dopamine receptor D2 stably expressed in CHO cells was evaluated using [3H]spiperone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50050464(3-(4-Phenyl-piperazin-1-ylmethyl)-1H-indole | CHEM...)
Affinity DataKi:  280nMAssay Description:Binding affinity towards cloned human Dopamine receptor D3 stably expressed in CHO cells was evaluated using [3H]spiperone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed