BDBM50051821 CHEMBL282379::[(S)-4-((R)-2-Amino-3-mercapto-propyl)-3-butyl-piperazin-1-yl]-phenyl-methanone

SMILES CCCC[C@H]1CN(CCN1C[C@@H](N)CS)C(=O)c1ccccc1

InChI Key InChIKey=XNUGRKDPRCDTJX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50051821   

TargetDimer of Protein farnesyltransferase subunit beta(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50051821([(S)-4-((R)-2-Amino-3-mercapto-propyl)-3-butyl-pip...)
Affinity DataIC50: 24nMAssay Description:Inhibition of [3H]FPP incorporation into Ha-Ras by FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed