BDBM50053113 (3-Biphenyl-2-ylmethyl-1-carbamoylmethyl-2-cyclopropyl-indolizin-8-yloxy)-acetic acid::CHEMBL121030

SMILES NC(=O)Cc1c(C2CC2)c(Cc2ccccc2-c2ccccc2)n2cccc(OCC(O)=O)c12

InChI Key InChIKey=RMLGAGWBUQOFMZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50053113   

TargetPhospholipase A2(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50053113((3-Biphenyl-2-ylmethyl-1-carbamoylmethyl-2-cyclopr...)
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant human secretory phospholipase A2 (sPLA2), chromogenic screening assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhospholipase A2(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50053113((3-Biphenyl-2-ylmethyl-1-carbamoylmethyl-2-cyclopr...)
Affinity DataIC50: 26nMAssay Description:Inhibitory activity against recombinant human secretory phospholipase A2 (s-PLA2) by phosphatidylcholine/deoxycholate assay (PC/DOC).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed