BDBM50053235 CHEMBL3330232

SMILES COc1ccc2[nH]c(nc2c1)-c1c(N[C@H]2CCCNC2)c2cc(Cl)sc2[nH]c1=O

InChI Key InChIKey=NTXWXFSAJRMWNA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50053235   

TargetSerine/threonine-protein kinase Chk1(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50053235(CHEMBL3330232)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of Chk1 (unknown origin) by luminescent ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50053235(CHEMBL3330232)
Affinity DataIC50: 328nMAssay Description:Inhibition of Aurora A (unknown origin) expressed in Escherichia coli by ZLYTETM assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed