BDBM50054121 3,3-Dimethyl-1-[4-(1,2,3,4-tetrahydro-naphthalen-1-yl)-butyl]-piperidine::CHEMBL128442

SMILES CC1(C)CCCN(CCCCC2CCCc3ccccc23)C1

InChI Key InChIKey=JAJILYYYWBUWHZ-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50054121   

TargetSigma non-opioid intracellular receptor 1(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50054121(3,3-Dimethyl-1-[4-(1,2,3,4-tetrahydro-naphthalen-1...)
Affinity DataIC50: 0.690nMAssay Description:Evaluated for the binding affinity towards sigma 1 receptor by displacing the radioligand [3H]-SKF- 10047 in whole rat brain membrane.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50054121(3,3-Dimethyl-1-[4-(1,2,3,4-tetrahydro-naphthalen-1...)
Affinity DataKi: >1.43E+3nMAssay Description:Binding affinity was tested on 5-hydroxytryptamine 1A receptor using radioligand [3H]5-HT binding assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50054121(3,3-Dimethyl-1-[4-(1,2,3,4-tetrahydro-naphthalen-1...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity was tested on Dopamine receptor D2 using radioligand [3H]spiroperidolMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed