BDBM50054501 2-[(S)-3-(Butane-1-sulfonylamino)-2-oxo-piperidin-1-yl]-N-((S)-3-carbamimidoyl-2-hydroxy-cyclohexyl)-acetamide::CHEMBL140545

SMILES CCCCS(=O)(=O)N[C@H]1CCCN(CC(=O)N[C@H]2CCCC(C2O)C(N)=N)C1=O

InChI Key InChIKey=HCCOVNMWPQQJTR-WJEHIRDRSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50054501   

TargetCoagulation factor X(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054501(2-[(S)-3-(Butane-1-sulfonylamino)-2-oxo-piperidin-...)
Affinity DataIC50:  2.50E+3nMAssay Description:In vitro for inhibition of Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAnionic trypsin(Bos taurus)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054501(2-[(S)-3-(Butane-1-sulfonylamino)-2-oxo-piperidin-...)
Affinity DataIC50:  2.50E+3nMAssay Description:compound was tested in vitro for inhibition of serine protease Trypsin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054501(2-[(S)-3-(Butane-1-sulfonylamino)-2-oxo-piperidin-...)
Affinity DataIC50:  709nMAssay Description:In vitro for inhibition of serine protease thrombin(FIIa).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed