BDBM50054543 (Z)-2-Cyano-3-hydroxy-4-methyl-penta-2,4-dienoic acid (4-trifluoromethyl-phenyl)-amide::2-cyano-3-hydroxy-4-methyl-N-(4-(trifluoromethyl)phenyl)penta-2,4-dienamide::CHEMBL141086

SMILES CC(=C)C(=O)C(C#N)C(=O)Nc1ccc(cc1)C(F)(F)F

InChI Key InChIKey=UFJNSGIBUJADFQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50054543   

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Mouse)
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50054543(2-cyano-3-hydroxy-4-methyl-N-(4-(trifluoromethyl)p...)
Affinity DataIC50: 195nMAssay Description:Inhibitory concentration tested on enzyme dihydroorotate dehydrogenase in mouseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rat)
Tunghai University

Curated by ChEMBL
LigandPNGBDBM50054543(2-cyano-3-hydroxy-4-methyl-N-(4-(trifluoromethyl)p...)
Affinity DataIC50: 251nMAssay Description:Inhibition of rat DHODHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rat)
Tunghai University

Curated by ChEMBL
LigandPNGBDBM50054543(2-cyano-3-hydroxy-4-methyl-N-(4-(trifluoromethyl)p...)
Affinity DataIC50: 251nMAssay Description:Inhibitory concentration tested against enzyme dihydroorotate dehydrogenase in ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed