BDBM50054580 (Z)-2-Cyano-3-cyclopentyl-3-hydroxy-N-(4-trifluoromethyl-phenyl)-acrylamide::2-cyano-3-cyclopentyl-3-hydroxy-N-(4-(trifluoromethyl)phenyl)acrylamide::CHEMBL143438

SMILES FC(F)(F)c1ccc(NC(=O)C(C#N)C(=O)C2CCCC2)cc1

InChI Key InChIKey=QGLCNGHFYRTBAV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50054580   

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Mouse)
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50054580(2-cyano-3-cyclopentyl-3-hydroxy-N-(4-(trifluoromet...)
Affinity DataIC50: 2.82E+4nMAssay Description:Inhibitory concentration tested on enzyme dihydroorotate dehydrogenase in mouseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rat)
Tunghai University

Curated by ChEMBL
LigandPNGBDBM50054580(2-cyano-3-cyclopentyl-3-hydroxy-N-(4-(trifluoromet...)
Affinity DataIC50: 3.16E+4nMAssay Description:Inhibition of rat DHODHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rat)
Tunghai University

Curated by ChEMBL
LigandPNGBDBM50054580(2-cyano-3-cyclopentyl-3-hydroxy-N-(4-(trifluoromet...)
Affinity DataIC50: 3.16E+4nMAssay Description:Inhibitory concentration tested against enzyme dihydroorotate dehydrogenase in ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed