BDBM50054758 CHEMBL357130::[2-(5-Benzyloxy-1H-indol-3-yl)-ethyl]-dimethyl-amine

SMILES CN(C)CCc1c[nH]c2ccc(OCc3ccccc3)cc12

InChI Key InChIKey=IDIJUWFVRXORPJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50054758   

Target5-hydroxytryptamine receptor 1D(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50054758([2-(5-Benzyloxy-1H-indol-3-yl)-ethyl]-dimethyl-ami...)
Affinity DataIC50: 25nMAssay Description:Displacement of [3H]-5-HT from human 5-hydroxytryptamine 1D receptor alpha expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50054758([2-(5-Benzyloxy-1H-indol-3-yl)-ethyl]-dimethyl-ami...)
Affinity DataIC50: 76nMAssay Description:Compound was tested for binding affinity against cloned human 5-hydroxytryptamine 1D receptor alpha expressed in CHO-K1 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50054758([2-(5-Benzyloxy-1H-indol-3-yl)-ethyl]-dimethyl-ami...)
Affinity DataIC50: 5.63E+3nMAssay Description:Antagonist activity at human TRPM8 receptor expressed in human T-REx-293 cells assessed as inhibition of menthol-induced 45calcium influx treated 5 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
LigandPNGBDBM50054758([2-(5-Benzyloxy-1H-indol-3-yl)-ethyl]-dimethyl-ami...)
Affinity DataIC50: 5.96E+3nMAssay Description:Antagonist activity at human TRPM8 receptor expressed in human T-REx-293 cells assessed as inhibition of icilin-induced 45calcium influx treated 5 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed