BDBM50054762 CHEMBL143512::Trifluoro-methanesulfonic acid 3-(2-amino-ethyl)-1H-indol-5-yl ester

SMILES NCCc1c[nH]c2ccc(OS(=O)(=O)C(F)(F)F)cc12

InChI Key InChIKey=GUJBOPKUKWHUKV-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50054762   

Target5-hydroxytryptamine receptor 1D(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50054762(Trifluoro-methanesulfonic acid 3-(2-amino-ethyl)-1...)
Affinity DataKi:  2.80nMAssay Description:Compound was tested for binding affinity against cloned human 5-hydroxytryptamine 1D receptor alpha expressed in CHO-K1 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50054762(Trifluoro-methanesulfonic acid 3-(2-amino-ethyl)-1...)
Affinity DataKi:  14nMAssay Description:Compound was tested for binding affinity against cloned human 5-hydroxytryptamine 1D receptor beta expressed in CHO-K1 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50054762(Trifluoro-methanesulfonic acid 3-(2-amino-ethyl)-1...)
Affinity DataKi:  18nMAssay Description:Compound was tested for intrinsic efficacy against human 5-hydroxytryptamine 1D receptor beta measured as the reduction of forskolin-stimulated cAMP.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50054762(Trifluoro-methanesulfonic acid 3-(2-amino-ethyl)-1...)
Affinity DataKi:  18nMAssay Description:Compound was tested for binding affinity against cloned human 5-hydroxytryptamine 1A receptor expressed in CHO-K1 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50054762(Trifluoro-methanesulfonic acid 3-(2-amino-ethyl)-1...)
Affinity DataKi:  19nMAssay Description:Compound was tested for intrinsic efficacy against human 5-hydroxytryptamine 1D receptor alpha measured as the reduction of forskolin-stimulated cAMP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50054762(Trifluoro-methanesulfonic acid 3-(2-amino-ethyl)-1...)
Affinity DataKi:  658nMAssay Description:Binding affinity for rat dopamine D2 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed