BDBM50055515 CHEMBL3317818

SMILES CC(C)(C)OC(=O)n1cnc(C[C@@H]2NC(=O)[C@]3(C)CSC(=N3)c3csc(CNC(=O)C[C@H](OC2=O)\C=C\CCS)n3)c1

InChI Key InChIKey=ZZWAMCDLANIKAG-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50055515   

TargetHistone deacetylase 1(Human)
Duke University

Curated by ChEMBL
LigandPNGBDBM50055515(CHEMBL3317818)
Affinity DataIC50: 0.620nMAssay Description:Inhibition of HDAC1 (unknown origin) incubated at 37 degC for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2016
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Duke University

Curated by ChEMBL
LigandPNGBDBM50055515(CHEMBL3317818)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of HDAC3 (unknown origin) incubated at 37 degC for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2016
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Duke University

Curated by ChEMBL
LigandPNGBDBM50055515(CHEMBL3317818)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of HDAC2 (unknown origin) incubated at 37 degC for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2016
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Duke University

Curated by ChEMBL
LigandPNGBDBM50055515(CHEMBL3317818)
Affinity DataIC50: 540nMAssay Description:Inhibition of HDAC8 (unknown origin) incubated at 37 degC for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2016
Entry Details Article
PubMed