BDBM50055516 CHEMBL3317817

SMILES CC(C)(C)OC(=O)NCCC[C@@H]1NC(=O)[C@]2(C)CSC(=N2)c2csc(CNC(=O)C[C@H](OC1=O)\C=C\CCS)n2

InChI Key InChIKey=GTUXNVSIYBGMNH-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50055516   

TargetHistone deacetylase 1(Human)
Duke University

Curated by ChEMBL
LigandPNGBDBM50055516(CHEMBL3317817)
Affinity DataIC50: 0.960nMAssay Description:Inhibition of HDAC1 (unknown origin) incubated at 37 degC for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2016
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Duke University

Curated by ChEMBL
LigandPNGBDBM50055516(CHEMBL3317817)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of HDAC2 (unknown origin) incubated at 37 degC for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2016
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Duke University

Curated by ChEMBL
LigandPNGBDBM50055516(CHEMBL3317817)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of HDAC3 (unknown origin) incubated at 37 degC for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2016
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Duke University

Curated by ChEMBL
LigandPNGBDBM50055516(CHEMBL3317817)
Affinity DataIC50: 790nMAssay Description:Inhibition of HDAC8 (unknown origin) incubated at 37 degC for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2016
Entry Details Article
PubMed