BDBM50055715 4-hydroxy-3-[4-hydroxy-2-oxo-2H-3-chromenyl(2-thienyl)methyl]-2H-2-chromenone::CHEMBL235961::CHEMBL82228

SMILES Oc1c(C(c2cccs2)c2c(O)c3ccccc3oc2=O)c(=O)oc2ccccc12

InChI Key InChIKey=VGJKTZUBVAMNAZ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50055715   

TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50055715(4-hydroxy-3-[4-hydroxy-2-oxo-2H-3-chromenyl(2-thie...)
Affinity DataIC50:  1.49E+5nMAssay Description:Integration of DNA by HIV -1 integraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50055715(4-hydroxy-3-[4-hydroxy-2-oxo-2H-3-chromenyl(2-thie...)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibitory activity against 3'-processing of DNA by HIV-1 integraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus type 1)TBA
LigandPNGBDBM50055715(4-hydroxy-3-[4-hydroxy-2-oxo-2H-3-chromenyl(2-thie...)
Affinity DataIC50:  6.76E+6nMAssay Description:Inhibition of Human immunodeficiency virus 1 integraseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetNAD(P)H dehydrogenase [quinone] 1(Human)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50055715(4-hydroxy-3-[4-hydroxy-2-oxo-2H-3-chromenyl(2-thie...)
Affinity DataIC50:  550nMAssay Description:Inhibition of human recombinant NQO1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD(P)H dehydrogenase [quinone] 1(Human)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50055715(4-hydroxy-3-[4-hydroxy-2-oxo-2H-3-chromenyl(2-thie...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human recombinant NQO1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50055715(4-hydroxy-3-[4-hydroxy-2-oxo-2H-3-chromenyl(2-thie...)
Affinity DataIC50:  1.10E+5nMAssay Description:Inhibitory activity against 3'-processing of DNA byHIV-1 integraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed