BDBM50055923 CHEMBL3321941::US9884814, Compound 269

SMILES COc1cc(Br)c(CC(=O)NC(=N)N[C@H](CC(C)C)C(=O)NCc2cccc(c2)-c2nnn[nH]2)cc1OC

InChI Key InChIKey=KLEHLFDSOCBYMG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50055923   

TargetCathepsin D(Human)
Merck Patent

US Patent
LigandPNGBDBM50055923(CHEMBL3321941 | US9884814, Compound 269)
Affinity DataIC50: 240nMpH: 5.5 T: 2°CAssay Description:In order to identify modulators of cathepsin D activity, a continuous enzymatic test was carried out with a synthetic peptide which carries a fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2018
Entry Details
US Patent

TargetCathepsin D(Human)
Merck Patent

US Patent
LigandPNGBDBM50055923(CHEMBL3321941 | US9884814, Compound 269)
Affinity DataIC50: 240nMAssay Description:Inhibition of human liver cathepsin D using MCA-labeled GKPILFFRLK(Dnp)-D-R-NH2 peptide by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2016
Entry Details Article
PubMed