BDBM50056136 CHEMBL3322162

SMILES Oc1ccc2c(CC(=O)N\N=C3/SCC(=O)N3c3c4CCCCc4nc4ccccc34)cc(=O)oc2c1

InChI Key InChIKey=RIKRBQRHKWZGBG-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50056136   

TargetAcetylcholinesterase(Human)
P. J. Safarik University

Curated by ChEMBL
LigandPNGBDBM50056136(CHEMBL3322162)
Affinity DataKi:  2.36E+3nMAssay Description:Inhibition of human recombinant AChE assessed as dissociation constant for enzyme-inhibitor complex by Lineweaver-Burk plotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2016
Entry Details Article
PubMed
TargetCholinesterase(Human)
P. J. Safarik University

Curated by ChEMBL
LigandPNGBDBM50056136(CHEMBL3322162)
Affinity DataIC50: 5.62E+3nMAssay Description:Inhibition of human BuChE pre-incubated for 5 mins before butylthiocholine substrate addition by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
P. J. Safarik University

Curated by ChEMBL
LigandPNGBDBM50056136(CHEMBL3322162)
Affinity DataIC50: 1.57E+4nMAssay Description:Inhibition of human recombinant AChE pre-incubated for 5 mins before acetylthiocholine substrate addition by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
P. J. Safarik University

Curated by ChEMBL
LigandPNGBDBM50056136(CHEMBL3322162)
Affinity DataKi:  6.53E+4nMAssay Description:Inhibition of human recombinant AChE assessed as dissociation constant for enzyme-inhibitor-substrate complex by Lineweaver-Burk plotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2016
Entry Details Article
PubMed