BDBM50056255 (6R,9S)-9-Mercaptomethyl-8-oxo-5,6,7,8,9,10,11,12,13,14,15,16-dodecahydro-7-aza-benzocyclotetradecene-6-carboxylic acid::CHEMBL423574

SMILES OC(=O)[C@H]1Cc2ccccc2CCCCCCC[C@H](CS)C(=O)N1

InChI Key InChIKey=VJXGETICKRSWGC-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50056255   

TargetNeprilysin(Human)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50056255((6R,9S)-9-Mercaptomethyl-8-oxo-5,6,7,8,9,10,11,12,...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration required to inhibit neutral endopeptidase (NEP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme(Human)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50056255((6R,9S)-9-Mercaptomethyl-8-oxo-5,6,7,8,9,10,11,12,...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration required to inhibit Angiotensin I converting enzyme (ACE)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeprilysin(Human)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50056255((6R,9S)-9-Mercaptomethyl-8-oxo-5,6,7,8,9,10,11,12,...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of neutral endopeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThermolysin(Bacillus thermoproteolyticus)
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50056255((6R,9S)-9-Mercaptomethyl-8-oxo-5,6,7,8,9,10,11,12,...)
Affinity DataIC50: 6.00E+4nMAssay Description:Inhibitory concentration required to inhibit thermolysinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThermolysin(Bacillus thermoproteolyticus)
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50056255((6R,9S)-9-Mercaptomethyl-8-oxo-5,6,7,8,9,10,11,12,...)
Affinity DataIC50: 6.00E+4nMAssay Description:Inhibitory concentration required to inhibit thermolysin (TLN)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed