BDBM50056518 6-{[(4-Benzenesulfinyl-3-chloro-phenyl)-prop-2-ynyl-amino]-methyl}-2-methyl-3H-quinazolin-4-one::CHEMBL160215

SMILES C#CCN(Cc1ccc2nc(C)[nH]c(=O)c2c1)c1ccc(S(=O)c2ccccc2)c(Cl)c1

InChI Key InChIKey=UYKAAMQABIZOIG-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50056518   

TargetThymidylate synthase(Human)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50056518BDBM50056518(6-{[(4-Benzenesulfinyl-3-chloro-phenyl)-prop-2-yny...)
Affinity DataKi:  27nMAssay Description:Binding affinity against recombinant human thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50056518BDBM50056518(6-{[(4-Benzenesulfinyl-3-chloro-phenyl)-prop-2-yny...)
Affinity DataKi:  27nMAssay Description:Binding affinity against recombinant human thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50056518BDBM50056518(6-{[(4-Benzenesulfinyl-3-chloro-phenyl)-prop-2-yny...)
Affinity DataKi:  54nMAssay Description:Binding affinity against recombinant thymidylate synthase in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed