BDBM50056996 6-Chloro-3-hydroxy-2-methyl-1,1-dioxo-1,2-dihydro-1lambda*6*-benzo[e][1,2]thiazine-4-carboxylic acid (2,4-difluoro-phenyl)-amide::CHEMBL177606

SMILES CN1C(=O)C(C(=O)Nc2ccc(F)cc2F)c2cc(Cl)ccc2S1(=O)=O

InChI Key InChIKey=ZRCZMHCAEFDMIM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50056996   

TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50056996(6-Chloro-3-hydroxy-2-methyl-1,1-dioxo-1,2-dihydro-...)
Affinity DataIC50:  300nMAssay Description:Concentration of drug that causes a 50% decrease in the maximal inhibition of Prostaglandin G/H synthase 2 activity as measured by PGE2 production('+...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50056996(6-Chloro-3-hydroxy-2-methyl-1,1-dioxo-1,2-dihydro-...)
Affinity DataIC50:  240nMAssay Description:Concentration of drug that causes a 50% decrease in the maximal inhibition of Prostaglandin G/H synthase 1 activity as measured by PGE2 production('+...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed