BDBM50057026 CHEMBL3326114

SMILES COc1ccc(OC)c(Sc2ccc3nnc(-c4ccccc4)n3n2)c1

InChI Key InChIKey=CXXFFIHMLWJXEX-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50057026   

LigandPNGBDBM50057026(CHEMBL3326114)
Affinity DataIC50: 40nMAssay Description:Inhibition of GST-tagged truncated LRRK2 (unknown origin) using fluorescein-labeled peptide LRRKtide as substrate by LANTHA screen assay in presence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/1/2016
Entry Details Article
PubMed
LigandPNGBDBM50057026(CHEMBL3326114)
Affinity DataIC50: 82nMAssay Description:Inhibition of LRRK2 G2019S mutant (unknown origin) using fluorescein-labeled peptide LRRKtide as substrate by LANTHA screen assay in presence of 1 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/1/2016
Entry Details Article
PubMed
LigandPNGBDBM50057026(CHEMBL3326114)
Affinity DataIC50: 173nMAssay Description:Inhibition of GST-tagged truncated LRRK2 (unknown origin) using fluorescein-labeled peptide LRRKtide as substrate by LANTHA screen assay in presence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/1/2016
Entry Details Article
PubMed
LigandPNGBDBM50057026(CHEMBL3326114)
Affinity DataIC50: 1.38E+3nMAssay Description:Inhibition of phosphorylation at S935 residue of wild-type full-length LRRK2 kinase (unknown origin) expressed in HEK 293 cells after 90 mins by ELIS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/1/2016
Entry Details Article
PubMed