BDBM50057552 4-[5-(5-Bromo-thiophen-2-yl)-3-trifluoromethyl-pyrazol-1-yl]-benzenesulfonamide::CHEMBL29472

SMILES NS(=O)(=O)c1ccc(cc1)-n1nc(cc1-c1ccc(Br)s1)C(F)(F)F

InChI Key InChIKey=TVETVUKIGCRVNH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50057552   

TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50057552(4-[5-(5-Bromo-thiophen-2-yl)-3-trifluoromethyl-pyr...)
Affinity DataIC50:  2.91E+3nMAssay Description:In vitro inhibitory concentration required to block recombinant human prostaglandin G/H synthase 1 (COX-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50057552(4-[5-(5-Bromo-thiophen-2-yl)-3-trifluoromethyl-pyr...)
Affinity DataIC50:  12.0nMAssay Description:Inhibition of human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50057552(4-[5-(5-Bromo-thiophen-2-yl)-3-trifluoromethyl-pyr...)
Affinity DataIC50:  12nMAssay Description:In vitro inhibitory concentration required to block human recombinant prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed