BDBM50057619 4-Chloro-5-(4-chloro-phenyl)-1-(4-sulfamoyl-phenyl)-1H-pyrazole-3-carboxylic acid methyl ester::CHEMBL28491

SMILES COC(=O)c1nn(c(c1Cl)-c1ccc(Cl)cc1)-c1ccc(cc1)S(N)(=O)=O

InChI Key InChIKey=MEBSTASXWKTLJD-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50057619   

TargetProstaglandin G/H synthase 2(Mouse)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50057619(4-Chloro-5-(4-chloro-phenyl)-1-(4-sulfamoyl-phenyl...)
Affinity DataIC50: 158nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50057619(4-Chloro-5-(4-chloro-phenyl)-1-(4-sulfamoyl-phenyl...)
Affinity DataIC50: 158nMAssay Description:Inhibition of human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50057619(4-Chloro-5-(4-chloro-phenyl)-1-(4-sulfamoyl-phenyl...)
Affinity DataIC50: 160nMAssay Description:In vitro inhibitory concentration required to block human recombinant prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50057619(4-Chloro-5-(4-chloro-phenyl)-1-(4-sulfamoyl-phenyl...)
Affinity DataIC50: 407nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 1 (COX-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50057619(4-Chloro-5-(4-chloro-phenyl)-1-(4-sulfamoyl-phenyl...)
Affinity DataIC50: 410nMAssay Description:In vitro inhibitory concentration required to block recombinant human prostaglandin G/H synthase 1 (COX-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed