BDBM50057826 (S)-1-((R)-2-Amino-3,3-dicyclohexyl-propionyl)-pyrrolidine-2-carboxylic acid (4-amino-cyclohexylmethyl)-amide::1-(2-Amino-3,3-dicyclohexyl-propionyl)-pyrrolidine-2-carboxylic acid (4-amino-cyclohexylmethyl)-amide::CHEMBL289395
SMILES N[C@H](C(C1CCCCC1)C1CCCCC1)C(=O)N1CCC[C@H]1C(=O)NCC1CCC(N)CC1
InChI Key InChIKey=SYJMIXHRYXUAGD-FEROLFGZSA-N
Data 8 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50057826
Affinity DataKi: 0.0560nMAssay Description:Inhibitory activity against human thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 0.0560nMAssay Description:Binding affinity against Thrombin.Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 120nMAssay Description:Inhibitory activity of the compound against human serine protease (Trypsin)(2143*)More data for this Ligand-Target Pair
Affinity DataKi: 5.00E+3nMAssay Description:Inhibitory activity of the compound against human serine protease (plasma Kallikrein)(89000*)More data for this Ligand-Target Pair
Affinity DataKi: 9.50E+4nMAssay Description:Inhibitory activity of the compound against human serine protease Coagulation factor X (1.7*10e6*)More data for this Ligand-Target Pair
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: 1.37E+5nMAssay Description:Inhibitory activity of the compound against human serine protease (TPA) (2.5*10e6*)More data for this Ligand-Target Pair
Affinity DataKi: 1.65E+5nMAssay Description:Inhibitory activity of the compound against human serine protease (plasmin) (3.0*10e6)More data for this Ligand-Target Pair
Affinity DataKi: 4.17E+5nMAssay Description:Inhibitory activity of the compound against human serine protease (act protein C )(7.5*10e6*)More data for this Ligand-Target Pair