BDBM50057974 4-[2-(3-Bromo-phenyl)-4-trifluoromethyl-imidazol-1-yl]-benzenesulfonamide::CHEMBL46584

SMILES NS(=O)(=O)c1ccc(cc1)-n1cc(nc1-c1cccc(Br)c1)C(F)(F)F

InChI Key InChIKey=DHRWMANEHKIRBS-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50057974   

TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50057974(4-[2-(3-Bromo-phenyl)-4-trifluoromethyl-imidazol-1...)
Affinity DataIC50:  4.50E+3nMAssay Description:Concentration required to inhibit human prostaglandin G/H synthase 1 (COX-1) by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
University Of Hyderabad

Curated by ChEMBL
LigandPNGBDBM50057974(4-[2-(3-Bromo-phenyl)-4-trifluoromethyl-imidazol-1...)
Affinity DataIC50:  7.07E+6nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50057974(4-[2-(3-Bromo-phenyl)-4-trifluoromethyl-imidazol-1...)
Affinity DataIC50:  7.08nMAssay Description:Inhibition of human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50057974(4-[2-(3-Bromo-phenyl)-4-trifluoromethyl-imidazol-1...)
Affinity DataIC50:  7nMAssay Description:Concentration required to inhibit human Prostaglandin G/H synthase 2 (COX-2) by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed