BDBM50058232 CHEMBL296506::N-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-3-methyl-benzamide

SMILES COc1ccccc1N1CCN(CNC(=O)c2cccc(C)c2)CC1

InChI Key InChIKey=JIXQPDNGVCMIOH-UHFFFAOYSA-N

Data  6 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50058232   

TargetD(4) dopamine receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50058232(CHEMBL296506 | N-[4-(2-Methoxy-phenyl)-piperazin-1...)
Affinity DataKi:  6.70nMAssay Description:Binding affinity for human Dopamine receptor D4 expressed in CHO K1 transfected cells using [3H]-Spiperone as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50058232(CHEMBL296506 | N-[4-(2-Methoxy-phenyl)-piperazin-1...)
Affinity DataKi:  6.76nMAssay Description:Binding affinity of compound towards human dopamine receptor D4 was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50058232(CHEMBL296506 | N-[4-(2-Methoxy-phenyl)-piperazin-1...)
Affinity DataKi:  12.9nMAssay Description:Binding affinity towards human dopamine receptor D4 expressed in CHO cells was determined by using [3H]thymidine as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50058232(CHEMBL296506 | N-[4-(2-Methoxy-phenyl)-piperazin-1...)
Affinity DataKi:  835nMAssay Description:Binding affinity for human Dopamine receptor D2 expressed in CHO K1 transfected cells using [3H]-Spiperone as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50058232(CHEMBL296506 | N-[4-(2-Methoxy-phenyl)-piperazin-1...)
Affinity DataKi:  2.45E+3nMAssay Description:Binding affinity towards human dopamine receptor D2 was determined by using [3H]spiperone as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50058232(CHEMBL296506 | N-[4-(2-Methoxy-phenyl)-piperazin-1...)
Affinity DataKi:  2.48E+3nMAssay Description:Binding affinity for human Dopamine receptor D3 expressed in CHO K1 transfected cells using [3H]-Spiperone as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50058232(CHEMBL296506 | N-[4-(2-Methoxy-phenyl)-piperazin-1...)
Affinity DataEC50:  13nMAssay Description:Agonist activation of human dopamine receptor stimulating mitogenesis in Dopamine receptor D4-transfected CHO pro-5 cells using [3H]-thymidine as rad...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed