BDBM50058760 CHEMBL3335421

SMILES O=C(Nc1ccc(cc1)C#CC1CCCCC1)c1ccc(CN2CCN(Cc3cccnc3)CC2)cc1

InChI Key InChIKey=VZXIZTQHELIFBK-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50058760   

TargetEndothelial PAS domain-containing protein 1/Hypoxia-inducible factor 1-alpha(Human)
Eisai

Curated by ChEMBL

LigandBDBM50058760(CHEMBL3335421)Copy SMILESCopy InChI

Affinity DataIC50: 3.10nMAssay Description:Inhibition of HIF1 signaling in human U251 cells expressing VEGF by VEGF promoter-driven PLAP reporter gene assayMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
4/2/2016
Entry Details Article
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