BDBM50058790 CHEMBL3327156

SMILES CSc1nc2ncnc(NCC(P(O)(O)=O)P(O)(O)=O)c2cc1-c1ccccc1

InChI Key InChIKey=CHHCOXBOQMCBLF-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50058790   

TargetReverse transcriptase(Human immunodeficiency virus type 1)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50058790(CHEMBL3327156)
Affinity DataIC50: 600nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase M184V mutant assessed as inhibition of DNA primer extension using [8-3H(N)]-dATP by scintillation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50058790(CHEMBL3327156)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase E89T mutant assessed as inhibition of DNA primer extension using [8-3H(N)]-dATP by scintillation p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50058790(CHEMBL3327156)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase assessed as inhibition of DNA primer extension using [8-3H(N)]-dATP by scintillation proximity ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50058790(CHEMBL3327156)
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase K65R mutant assessed as inhibition of DNA primer extension using [8-3H(N)]-dATP by scintillation p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed