BDBM50058810 Methyl Ursolate::Ursolic Acid Methyl Ester

SMILES [H][C@@]12CC[C@]3(C)[C@]([H])(CC=C4[C@]5([H])[C@@H](C)[C@H](C)CC[C@@]5(CC[C@@]34C)C(=O)OC)[C@@]1(C)CC[C@H](O)C2(C)C

InChI Key InChIKey=YCBSMEKEDOHEQI-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50058810   

TargetCathepsin D(Human)TBA
LigandPNGBDBM50058810(Methyl Ursolate | Ursolic Acid Methyl Ester)
Affinity DataIC50: 9.45E+3nMAssay Description:Inhibition of cathepsin D (unknown origin) using hemoglobin as substrate after 30 min by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article

TargetCarbonic anhydrase 2(Bovine)
Martin-Luther-Universit£T Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50058810(Methyl Ursolate | Ursolic Acid Methyl Ester)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of bovine erythrocyte carbonic anhydrase 2 using 4-nitrophenyl acetate substrate by photometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 7(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50058810(Methyl Ursolate | Ursolic Acid Methyl Ester)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human USP7 using human N-terminal GST-tagged UBA52 as substrate preincubated for 10 mins followed by substrate addition measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed