BDBM50059206 CHEMBL3393321

SMILES FC(F)(F)c1ccnc(Nc2cc(nc(n2)N2CCC(F)(F)C2)C2CCCNC2)c1

InChI Key InChIKey=SKVWGAYKWDVXNG-UHFFFAOYSA-N

Data  1 KI  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50059206   

TargetMitogen-activated protein kinase kinase kinase 12(Human)
Genentech

Curated by ChEMBL

LigandBDBM50059206(CHEMBL3393321)Copy SMILESCopy InChI

Affinity DataKi:  7nMAssay Description:Inhibition of DLK (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
4/2/2016
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL

TargetMitogen-activated protein kinase kinase kinase 12(Human)
Genentech

Curated by ChEMBL

LigandBDBM50059206(CHEMBL3393321)Copy SMILESCopy InChI

Affinity DataIC50: 408nMAssay Description:Inhibition of human DLK transfected in HEK293 cells assessed as JNK phosphorylation after 5.5 hrs by Hoechst-33342 staining-based assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
4/2/2016
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL