BDBM50059209 CHEMBL3393317

SMILES Cc1nc(Nc2cc(ccn2)C#N)cc(n1)C1CCCN(C1)C(=O)c1ccccc1

InChI Key InChIKey=BLBAMJMJBNCHSZ-UHFFFAOYSA-N

Data  1 KI  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50059209   

TargetMitogen-activated protein kinase kinase kinase 12(Human)
Genentech

Curated by ChEMBL

LigandBDBM50059209(CHEMBL3393317)Copy SMILESCopy InChI

Affinity DataKi:  90nMAssay Description:Inhibition of DLK (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
4/2/2016
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL

TargetMitogen-activated protein kinase kinase kinase 12(Human)
Genentech

Curated by ChEMBL

LigandBDBM50059209(CHEMBL3393317)Copy SMILESCopy InChI

Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human DLK transfected in HEK293 cells assessed as JNK phosphorylation after 5.5 hrs by Hoechst-33342 staining-based assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
4/2/2016
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL