BDBM50059211 CHEMBL3393314

SMILES CC(C)c1ccnc(Nc2cc(nc(C)n2)C2CCCN(C2)C(=O)c2ccccc2)c1

InChI Key InChIKey=ROSFWOBLBMDAEV-UHFFFAOYSA-N

Data  1 KI  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50059211   

TargetMitogen-activated protein kinase kinase kinase 12(Human)
Genentech

Curated by ChEMBL

LigandBDBM50059211(CHEMBL3393314)Copy SMILESCopy InChI

Affinity DataKi:  4nMAssay Description:Inhibition of DLK (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
4/2/2016
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL

TargetMitogen-activated protein kinase kinase kinase 12(Human)
Genentech

Curated by ChEMBL

LigandBDBM50059211(CHEMBL3393314)Copy SMILESCopy InChI

Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human DLK transfected in HEK293 cells assessed as JNK phosphorylation after 5.5 hrs by Hoechst-33342 staining-based assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
4/2/2016
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL