BDBM50059217 1-Benzyl-4-[5-(4-chloro-phenyl)-1H-pyrazol-3-yl]-4-methyl-piperidine::CHEMBL80207

SMILES CC1(CCN(Cc2ccccc2)CC1)c1cc(n[nH]1)-c1ccc(Cl)cc1

InChI Key InChIKey=UOIRCOOXVJGCIE-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50059217   

TargetD(4) dopamine receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50059217(1-Benzyl-4-[5-(4-chloro-phenyl)-1H-pyrazol-3-yl]-4...)
Affinity DataKi:  47nMAssay Description:Ability to displace [3H]spiperone from human dopamine receptor D4 (hD4) receptor stably expressed in HEK293 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50059217(1-Benzyl-4-[5-(4-chloro-phenyl)-1H-pyrazol-3-yl]-4...)
Affinity DataKi:  240nMAssay Description:Ability to displace [3H]spiperone from human dopamine receptor D2 stably expressed in CHO cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50059217(1-Benzyl-4-[5-(4-chloro-phenyl)-1H-pyrazol-3-yl]-4...)
Affinity DataKi:  1.30E+3nMAssay Description:Ability to displace [3H]spiperone from human dopamine receptor D3 (hD3) receptor stably expressed in HEK293 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed