BDBM50059750 7,8-Dihydro-benzo[k]phenanthridine-6-carboxylic acid benzyl-methyl-amide::CHEMBL15237

SMILES CN(Cc1ccccc1)C(=O)c1nc2ccccc2c-2c1CCc1ccccc-21

InChI Key InChIKey=JNBHOAKDJGYQGY-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50059750   

TargetTranslocator protein(Rat)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50059750(7,8-Dihydro-benzo[k]phenanthridine-6-carboxylic ac...)
Affinity DataIC50: 8.90nMAssay Description:In vitro binding affinity (pIC50) was tested against peripheral benzodiazepine receptor (PBR) in rat.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2012
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50059750(7,8-Dihydro-benzo[k]phenanthridine-6-carboxylic ac...)
Affinity DataIC50: 8.90nMAssay Description:In vitro displacement of [3H]PK11195 from the peripheral benzodiazepine receptor (PBR) in rat cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2012
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50059750(7,8-Dihydro-benzo[k]phenanthridine-6-carboxylic ac...)
Affinity DataIC50: 8.90nMAssay Description:Displacement of [3H]PK11195 from TSPO receptor in rat brain cortex membrane incubated for 120 mins by liquid scintillation spectrometer methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetTranslocator protein(Rat)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50059750(7,8-Dihydro-benzo[k]phenanthridine-6-carboxylic ac...)
Affinity DataIC50: 8.90nMAssay Description:Test in vitro, for potential ability to displace [3H]1 from PBR in rat brain cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed