BDBM50059860 ((2E,6E)-1-Hydroxy-3,7,11-trimethyl-dodeca-2,6,10-trienyl)-phosphonic acid::CHEMBL26180::Hydroxy phosphonate, 1
SMILES [#6]-[#6](-[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](/[#6])-[#6])-[#6]-[#6](=O)P([#8])([#8])=O
InChI Key InChIKey=NDLOFZNDXKZSBO-UKTHLTGXSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50059860
Affinity DataKi: 4.70nMAssay Description:Assay using farnesyl-ras-CVLS as the protein acceptor substrate.More data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Human)
Warner-Lambert
Curated by ChEMBL
Warner-Lambert
Curated by ChEMBL
Affinity DataKi: 5.20nMAssay Description:Inhibitory activity against farnesyl pyrophosphateMore data for this Ligand-Target Pair
Affinity DataKi: 5.20nMAssay Description:FPTase activity was assayed in the biosynthetically forward direction at 30C.More data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Bovine)
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 410nMAssay Description:Inhibition of farnesyl protein transferase from bovine brainMore data for this Ligand-Target Pair
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of squalene synthase from rat liver microsomesMore data for this Ligand-Target Pair