BDBM500603 7-((5-(3,8- diazabicyclo [3.2.1]octan-3- yl)pyridin-2- yl)amino)-4- (1-methyl-1H- pyrrolo[2,3- b]pyridin-4- yl)-2,3-dihydro- 1H-pyrrolo[3,4- c]pyridin-1- Fone::US11021481, Compound I-262::US11078201, Compound I-262::US11548890, Compound I-262

SMILES Cn1ccc2c(ccnc12)-c1ncc(Nc2ccc(cn2)N2CC3CCC(C2)N3)c2C(=O)NCc12

InChI Key InChIKey=DTAZQGKPEQUSGF-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 500603   

LigandPNGBDBM500603(US11021481, Compound I-262 | 7-((5-(3,8- diazabicy...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

LigandPNGBDBM500603(US11021481, Compound I-262 | 7-((5-(3,8- diazabicy...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

LigandPNGBDBM500603(US11021481, Compound I-262 | 7-((5-(3,8- diazabicy...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent

LigandPNGBDBM500603(US11021481, Compound I-262 | 7-((5-(3,8- diazabicy...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2022
Entry Details
US Patent

LigandPNGBDBM500603(US11021481, Compound I-262 | 7-((5-(3,8- diazabicy...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details
US Patent