BDBM50060812 CHEMBL3394735::US9458172, 3

SMILES Fc1cc(F)cc(c1)S(=O)(=O)c1ccc(CNC(=O)c2cc3cnccc3[nH]2)nc1

InChI Key InChIKey=XHYCUBHLLDKHDF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50060812   

TargetNicotinamide phosphoribosyltransferase(Human)
TBA

US Patent
LigandPNGBDBM50060812(US9458172, 3 | CHEMBL3394735)
Affinity DataIC50: 19.9nMpH: 7.5Assay Description:The NAMPT Enzymatic Reaction. The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
TBA

US Patent
LigandPNGBDBM50060812(US9458172, 3 | CHEMBL3394735)
Affinity DataIC50: 39nMAssay Description:Inhibition of human C-terminal His6-tagged NAMPT expressed in Escherichia coli Rosetta(DE3) incubated for 15 mins prior to substrate addition measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2016
Entry Details Article
PubMed