BDBM50061018 CHEMBL3393546::US9732087, 44

SMILES CN1CCN(CC1)c1ccnc(NC2CC3CCC2C3)n1

InChI Key InChIKey=IVFQODBYXHLMLR-UHFFFAOYSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50061018   

TargetHistamine H4 receptor(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50061018(CHEMBL3393546 | US9732087, 44)
Affinity DataEC50:  20nMAssay Description:Agonist activity at human recombinant histamine H4 receptor expressed in SK-N-MC cells assessed as effect on forskolin-stimulated cAMP-mediated repor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2016
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50061018(CHEMBL3393546 | US9732087, 44)
Affinity DataKi:  31.5nMAssay Description:Cell pellets from SK-N-MC cells stably or transiently transfected with human H4 receptor (NCBI accession No. AF312230) were used for the binding assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent

TargetHistamine H4 receptor(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50061018(CHEMBL3393546 | US9732087, 44)
Affinity DataKi:  86nMAssay Description:Displacement of [3H]histamine from human recombinant histamine H4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2016
Entry Details Article
PubMed