BDBM50061086 (2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-{2-[(3-chloro-propane-1-sulfonyl)-propyl-amino]-ethyl}-2-(3-fluoro-4-methoxy-phenyl)-pyrrolidine-3-carboxylic acid::CHEMBL325581
SMILES CCCN(CCN1C[C@@H]([C@H]([C@@H]1c1ccc(OC)c(F)c1)C(O)=O)c1ccc2OCOc2c1)S(=O)(=O)CCCCl
InChI Key InChIKey=IPZKGERDMRMXJO-VANUSSGQSA-N
Data 7 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50061086
Affinity DataIC50: 0.200nMAssay Description:Ability to displace endothelin ([125I]-ET-3) from endothelin B receptor derived from cerebellar tissue of porcine.More data for this Ligand-Target Pair
Affinity DataIC50: 0.140nMAssay Description:Binding assay performed using human Endothelin B receptor (hETB) expressed in chinese hamster ovary cells(CHO)More data for this Ligand-Target Pair
Affinity DataIC50: 0.550nMAssay Description:Ability of the compound to block the ET-1-induced hydrolysis of inositol phosphate in Endothelin A receptor of MMQ cells.More data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Ability to displace endothelin ([125I]-ET-3) from endothelin B receptor derived from cerebellar tissue of porcine.More data for this Ligand-Target Pair
Affinity DataIC50: 0.830nMAssay Description:Ability of the compound to block the ET-1-induced hydrolysis of inositol phosphate in Endothelin B receptor of chinese hamster ovary(CHO) cells.More data for this Ligand-Target Pair
Affinity DataIC50: 0.0700nMAssay Description:Binding assay performed using human Endothelin A receptor (hETA) expressed in chinese hamster ovary cells(CHO).More data for this Ligand-Target Pair
Affinity DataIC50: 0.0940nMAssay Description:Ability to displace endothelin ([125I]-ET-1) from endothelin A receptor derived from MMQ cells of rodent.More data for this Ligand-Target Pair